禁漫天堂

课题组网站：//macbio.jinman123.net/

学历及学术经历: 

2007年本科毕业于武汉理工大学高分子材料与工程专业，随后在本校保送直博，2012年7月获得武汉理工大学生物材料学博士学位（博士生导师：陈红教授）。2012年8月加入禁漫天堂 高分子科学与工程系，并于2015年7月晋升为副教授。2019.09-2020.09新加坡国立大学访问学者。2024年7月晋升为教授。先后担任国际期刊Polymer Chemistry和Colloids and Surfaces B: Biointerfaces编辑助理。

研究领域: 生物材料表面改性及功能化；蛋白质、细胞与材料表面的相互作用研究；多功能血液接触材料表面的构建；高分子材料表面的类肝素化研究；微流控芯片材料表面改性及生物功能化

主要荣誉：

2019、2023年江苏省大学生创新创业训练计划项目指导教师

2020年江苏省科技副总

2021年江苏省“青蓝工程”优秀青年骨干教师培养对象

2021年苏州大学本科毕业设计（论文）优秀指导教师

2021年江苏省本科优秀毕业论文（设计）一等奖指导教师

2022年第二届苏州大学教师教学创新大赛一等奖

2023年第三届苏州大学教师教学创新大赛一等奖

近年主持的科研项目：

(1) 血液接触界面功能高分子材料的研发（横向项目），2024.8-2027.7，项目负责人。

(2) 国家自然科学基金面上项目，2021.01-2024.12，项目负责人。

(3) 材料表面改性技术的开发（横向项目），2020.7-2023.7，项目负责人。

(4) 国家自然科学基金面上项目，2018.01-2021.12，项目负责人。

(5) 国家自然科学基金青年科学基金项目，2014.01-2016.12，项目负责人。

(6) 江苏省高校自然科学研究面上项目，2013.08-2015.12，项目负责人。

(7) 中国博士后科学基金面上资助，2013.09-2016.12，项目负责人。

代表性论文：

[1]      H. Wang, H. Wang*, X. Liu*, Z. Zhang*. Anticoagulation colloidal microrobots based on heparin-mimicking polymers. Journal of Colloid and Interface Science, 2025: 137345.

[2]      S. Zhang, J. Sun, S. Guo, Y. Wang, Y. Zhang, J. Lei, X. Liu*, H. Chen*. Balancing functions of antifouling, nitric oxide release and vascular cell selectivity for enhanced endothelialization of assembled multilayers. Regenerative Biomaterials, 2024, 11: rbae096.

[3]      Q. Wu, S. Guo, X. Liang, W. Sun, J. Lei, L. Pan, X. Liu*, H. Chen*. Endothelium-inspired hemocompatible silicone surfaces: an elegant balance between antifouling properties and endothelial cell selectivity. Biomacromolecules, 2024, 25: 7202-7215.

[4]      C. Jiang, W. Sun, Q. Wu, X. Liang, J. Lei, S. Zhang, D. Sheng, F. Zhou*, X. Liu*, H. Chen. Patterned growth of vascular cells on chemically heterogeneous surfaces modified with heparin-mimicking polymers. European Polymer Journal, 2024, 211: 113011.

[5]      D. Fan, X. Liu*, H. Chen*. Endothelium-mimicking materials: a “rising star” for antithrombosis. ACS Applied Materials & Interfaces, 2024, 16: 53343-53371.

[6]      W. Sun, X. Liang, J. Lei, C. Jiang, D. Sheng, S. Zhang, X. Liu*, H. Chen. Regulating cell behavior via regional patterned distribution of heparin-like polymers. Biomaterials Advances, 2023, 154: 213664.

[7]      R. Mei, X. Heng, X. Liu*, G. Chen*. Glycopolymers for antibacterial and antiviral applications. Molecules, 2023, 28: 985.

[8]      J. Lei, W. Sun, D. Sheng, S. Wang, X. Liu*, T. Zhao, H. Chen*. Effect of structural elements of heparin-mimicking polymers on vascular cell distribution and functions: chemically homogeneous or heterogeneous? ACS Biomaterials Science & Engineering, 2023, 9: 5304-5311.

[9]      J. Feng, J. Wang, H. Wang, X. Cao, X. Ma, Y. Rao, H. Pang, S. Zhang, Y. Zhang, L. Wang, X. Liu*, H. Chen*. Multistage anticoagulant aurfaces: a synergistic combination of protein resistance, fibrinolysis, and endothelialization. ACS Applied Materials & Interfaces, 2023, 15: 35860-35871.

[10]   J. Chang, L. Yu*, J. Lei, X. Liu*, C. Li, Y. Zheng, H. Chen*. A multifunctional bio-patch crosslinked with glutaraldehyde for enhanced mechanical performance, anti-coagulation properties, and anti-calcification properties. Journal of Materials Chemistry B, 2023, 11: 10455.

[11]   X. Liang, A. Zhang, W. Sun, J. Lei, X. Liu*, Z. Tang, H. Chen. Vascular cell behavior on glycocalyx-mimetic surfaces: simultaneous mimicking of the chemical composition and topographical structure of the vascular endothelial glycocalyx. Colloids and Surfaces B: Biointerfaces, 2022, 212: 112337.

[12]   A. Zhang, W. Sun, X. Liang, X. Chen, Y. Li, X. Liu*, H. Chen*. The role of carboxylic groups in heparin-mimicking polymer-functionalized surfaces for blood compatibility: Enhanced vascular cell selectivity. Colloids and Surfaces B: Biointerfaces, 2021, 201: 111653.

[13]   Y. Li, W. Sun, A. Zhang, S. Jin, X. Liang, Z. Tang, X. Liu*, H. Chen. Vascular cell behavior on heparin-like polymers modified silicone surfaces: The prominent role of the lotus leaf-like topography. Journal of Colloid and Interface Science, 2021, 603: 501-510.

[14]   W. Sun, S. Jin, A. Zhang, J. Huang, Y. Li, X. Liu*, H. Chen*. Vascular cell responses to silicone surfaces grafted with heparin-like polymers: surface chemical composition vs. topographic patterning. Journal of Materials Chemistry B, 2020, 8: 9151-9161.

[15]   S. Jin, J. Huang, X. Chen, H. Gu, D. Li*, A. Zhang, X. Liu*, H. Chen. Nitric oxide-generating antiplatelet polyurethane surfaces with multiple additional biofunctions via cyclodextrin-based host-guest interactions. ACS Applied Bio Materials, 2020, 3: 570-576.

[16]   J. Wu, C. Hu, Z. Tang, Q. Yu, X. Liu*, H. Chen. Tissue-engineered vascular grafts: balance of the four major requirements. Colloid and Interface Science Communications, 2018, 23: 34-44.

[17]   S. Li, B. Liu, T. Wei, C. Hu, Y. Hang, Y. Dong, X. Liu*, H. Chen*. Microfluidic channels with renewable and switchable biological functionalities based on host–guest interactions. Journal of Materials Chemistry B, 2018, 6: 8055-8063.

[18]   S. Jin, H. Gu, X. Chen, X. Liu*, W. Zhan, T. Wei, X. Sun*, C. Ren, H. Chen. A facile method to prepare a versatile surface coating with fibrinolytic activity, vascular cell selectivity and antibacterial properties. Colloids and Surfaces B: Biointerfaces, 2018, 167: 28-35.

[19]   X. Chen, H. Gu, Z. Lyu, X. Liu*, L. Wang*, H. Chen, J.L. Brash. Sulfonate groups and saccharides as essential structural elements in heparin-mimicking polymers used as surface modifiers: optimization of relative contents for antithrombogenic properties. ACS Applied Materials & Interfaces, 2018, 10: 1440-1449.

[20]   M. Wang, X. Liu*, Z. Lyu, H. Gu, D. Li, H. Chen. Glycosaminoglycans (GAGs) and GAG mimetics regulate the behavior of stem cell differentiation. Colloids and Surfaces B: Biointerfaces, 2017, 150: 175-182.

[21]   H. Gu, X. Chen, Q. Yu, X. Liu*, W. Zhan, H. Chen*, J.L. Brash. A multifunctional surface for blood contact with fibrinolytic activity, ability to promote endothelial cell adhesion and inhibit smooth muscle cell adhesion. Journal of Materials Chemistry B, 2017, 5: 604-611.

[22]   H. Gu, X. Chen, X. Liu*, W. Zhan, Z. Lyu, Q. Yu, Z. Wu*, H. Chen. A hemocompatible polyurethane surface having dual fibrinolytic and nitric oxide generating functions. Journal of Materials Chemistry B, 2017, 5: 980-987.

[23]   X. Liu, L. Yuan, D. Li, Z. Tang, Y. Wang, G. Chen, H. Chen*, J.L. Brash*. Blood compatible materials: state of the art. Journal of Materials Chemistry B, 2014, 2: 5718-5738.

[24]   J. Du, X. Liu*, W. Liu, Z. Wu*, H. Chen. One-step preparation of vinyl-functionalized material surfaces: a versatile platform for surface modification. Science China Chemistry, 2014, 57: 654-660.

[25]   Y. Wang, F. Zhou, X. Liu*, L. Yuan, D. Li, Y. Wang, H. Chen*. Aptamer-modified micro/nanostructured surfaces: efficient capture of Ramos cells in serum environment. ACS Applied Materials & Interfaces, 2013, 5: 3816-3823.